Diabetic nephropathy is the most serious complication of diabetes, and it is easier developed into end stage of renal disease which is more difficult in treatment than other kinds of kidney disease. So a timely treatment for diabetic nephropathy is necessary.
Cause
Diabetic nephropathy is caused by primary or secondary factor (such as: genetic and environmental factors, the absolute and relative lack of insulin, insulin resistance, hyperglycemia, abnormal metabolic syndrome). At the same time because of the body's immune regulating function obstacle, blood glucose get higher, and a series of lesion appear in the glomerular inherent cells, resulting in the glomerular basement membrane thickening and luminal stenosis, vasoconstriction, microcirculation disorder, and kidney chemia hypoxia. The damages of capillaries around the glomerular and renal tubular lead to further inflammation invasion and renal fibrosis. The synthesis of a large amount of extracellular matrix replace the healthy kidney inherent cells, and finally develop into glomerular sclerosis and necrosis.
The Stage of Diabetic nephropathy
1. High glomerular filtration and renal hypertrophy stage
2. Normal albuminuria stage
3. Continuous microalbuminuria stage
4. The clinical diabetic nephropathy stage
5. End-stage renal disease
Clinical Situation
Diabetic nephropathy is often appear with some complications of microvascular disease of other organs or systems such as diabetic retinopathy and peripheral neuropathy.
moreAt early stage of Diabetic Nephropathy, there are not some obvious symptoms. But once some abnormal symptoms bothered you, which means you are in a serious period.
* proteinuria
Barrier function of glomerular electronegative nuclear can't effectively stop the leakage of protein
* Hypertention
Hypertention is mainly caused by the increasing retention of fluids and sodium in body.
* High cholesterol levels
Protein loss caused the Increased cholesterol levels.
* Swelling
It is mainly attributable to retention of fluids and sodium in body.
* Poor appetite
The kidneys fail to filter out urea nitrogen from body which can be decomposed into ammonia with the help of urease. Ammonia can irritate gastrointestinal mucosa, finally leading to nausea, vomiting and poor appetite.
* Weight loss
Limiting intake of proteins and suffering from nausea, vomiting and poor appetite, patients would get weight loss.
* Fatigue
It is mainly due to anemia.
moreAfter years’research and practice, our experts have made a big improvement in treating the diabetic nephropathy, providing an advanced and systemic treatment method to patient.
Immunotherapy
Immunotherapy could be divided into six stage
1. Immune special examination and diagnosis, which means we will have a fully tests including the factors such as blood and urine ,location kidney damage ,Uremia ,complement ,Lymph cell subgroup, Protein electrophoresis,Urine protein alternative index, blood fat , blood lipid and so on
2.Immune blocking
Reduce the infiltration of the inflammatory cell,
Reduce the synthetic and release of the inflammatory madiator; Cytostatic T cell and B cell activity
Refrain the inflammatory reaction to avoid of immune complex generation
Anti inflammation and anti fibrosis
Clear the T cell out to block the generation of (producrion of)the auto antibody
Block the B cell to change to plasma cell
3. Immune Clearance
Plasma adsorption
Leukocyte adsorption
isolated ultrafiltration
Ascite filtration concentration
Immune adsorption
Blood lipid evolution
4. Immune tolerance
Use some medicines in small dosage regulally
5.Immune adjustment
Micro-Chinese Medicine Osmotherapy : through the functions of expanding blood vessel, anti inflammation, anti coagulation to degradate fibrosis.
Medicated Bath : Inducing diaphoresis to eliminate pathogenic factor and supporting genuine Qi, improve the immunity, expel the circulation and metabolic product from skin
Pedicure ：Doing the treatment by herb medicine, through the acupoint of feet.
6.Immune Protection
Use Treg cell to replace the damaged tissues and cells, then combine together with Chinese traditional medicine to rebuild the blood caillary and repair the the kidney to reverse it kidney function.
moreA healthy lifestyle is very important to control the physical condition. Patients especially should pay attention to their diet and daily life.
Diet
Protein supply:
In order to control the worsening renal function,the patients should control protein intake, choose high quality rich in protein diet.
Vitamin intake:
Kidney failure patients with high creatinine appropriate chooses food rich in vitamin A, vitamin B2, vitamin C .
Salt intake:
Low-salt diet can benefit the control of blood pressure as well as relieve swelling and slow kidney function deterioration. The patients with Diabetic Nephropathy are recommended to limit salt intake to 5 grams a day. Meanwhile, foods loaded in salt such as processed foods, cured foods should also be avoided.
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